Department of Mathematics
"A mathematical modelling
approach of Quorum Sensing"
By
MELTEM GÖLGELİ
(BİLKENT UNIVERSITY)
Abstract: Quorum sensing, a special kind of cell–cell
communication, has originally been described for well-mixed homogeneous
bacterial cultures. However, recent perception supports its ecological
relevance for spatially heterogeneous distributed cells, like colonies and
biofilms. New
experimental techniques allow for single cell analysis under these conditions,
which is crucial to understanding the effect of chemical
gradients and intercell variations. Based on a
reaction-diffusion system,
we develop a method that drastically reduces the computational complexity of
the model. In comparison to similar former approaches, handling and scaling is
much easier. Via a suitable scaling, this approach leads to approximative
algebraic equations for the stationary case. This approach can be easily used
for numerical situations.
Date: Monday, April 18, 2016
Time: 15:40
Place: Mathematics Seminar Room, SA-141
Tea and cookies will be served before the
seminar.
All are cordially invited