Department of
Molecular Biology
and Genetics

Bilkent University
Bilkent University
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Özlen KONU, Ph.D.

Assistant Professor

Mailing
Address
: Bilkent University
Faculty of Science, B Building
Department of
    Molecular Biology and Genetics
06800 Ankara, TURKEY
Phone : +90 312 290 2123
Fax : +90 312 290 5097
Email : konufen.bilkent.edu.tr

Biosketch

2002- Faculty Member
Molecular Biology and Genetics,
Bilkent University, Ankara, Turkey
2000-2002 Post-doctoral Trainee
Pharmacology,
University of Tennessee at Memphis TN, USA
1990-1992;
1994-1999
Teaching Assistant
Biological Sciences,
Texas Tech University, Lubbock TX, USA
1999 Ph.D.
Biology
Texas Tech University, Lubbock TX, USA
1992 M.Sc.
Biology
Texas Tech University, Lubbock TX, USA
1988-1989 Research Assistant
Biological Sciences
Texas Tech University, Lubbock TX, USA
1987 B.Sc.
METU, Ankara, Turkey

Research Interest

Applications of gene expression microarray technology for understanding of cellular signaling pathways.
Our research focuses on determining coordinated changes in the transcriptome when cholinergic signaling is modified via RNAi or agonists like nicotine. We perform comparative expression profiling among cell lines and gene network analyses to understand functional implications of cholinergic signaling in cancer and neuronal cells. Functional analyses we conduct include validation of microarray results at the mRNA, protein and metabolic activity as well as development of in vivo validation models using zebrafish xenotransplant and transgenic animal studies.
Development of methods for statistical, functional and meta analysis of microarray datasets.
Research in the lab focuses on finding novel ways for meta-analysis of expression datasets for mRNA and microRNAs through development of web interfaces for multivariate visualization, data extraction and gene prioritization. We are also interested in comparing transcriptomes of zebrafish and mammals for deciphering conserved signaling pathways in response to anticancer drugs and other modulators of physiology.

Lab Members


Department of Molecular Biology and Genetics
Faculty of Science, B Building
Bilkent University
Ankara, Turkey (06800)


Phone: +90 312 290 22 40
Fax: +90 312 266 50 97
E-mail: yildizfen.bilkent.edu.tr