Group Leader

Assist. Prof. Özlen Konu, Ph.D.

Mailing Address

Bilkent University
Faculty of Science, B Building
Department of Molecular Biology and Genetics
06800 Ankara, TURKEY

Office

Science B 245

Telephone

+90-312-290 21 23

Fax

+90-312-266 50 97

e-mail

Research Interests

  • Gene networks involved in nicotine’s pharmacological effects
  • Statistical and functional analysis of microarray experiments
  • Molecular, physiological and morphological correlates of development and feeding behavior in zebrafish.

Academic Degrees and Employment

  • Faculty member at the Dept. of Molecular Biology and Genetics, Bilkent Univ., Ankara, Turkey (2002-)
  • Postdoctoral research trainee, Department of Pharmacology, University of Tennessee, Memphis, TN, USA (2000-2002)
  • Ph.D. in Biology, Texas Tech University, Lubbock, TX, USA (1996-1999)
  • M.Sc. in Biology, Texas Tech University, Lubbock, TX, USA (1990-1992)
  • B.Sc. Department of Biology, METU Ankara, Turkey (1987)

Publications

  • Wang J, Gutala R, Hwang YY, Kim JM, Konu O, Ma JZ, Li MD (2007). Strain- and region-specific gene expression profiles in mouse brain in response to chronic nicotine treatment.Genes Brain Behav. PMID:17504244
  • Aydin TI, Tokcaer Z, Dalgic A, Konu O, Akcali KC (2007) Cloning and expression profile of FLT3 gene during rat progenitor cell dependent liver regeneration. Accepted J Gastroenterol Hepatol.
  • Dalkic E, Kuscu C, Sucularli C, Aydin TI., Akcali KC, Konu O. (2006) Alternatively Spliced Robo2 Isoforms in Zebrafish and Rat. Dev Genes Evol. 216(9):555-63. PMID:16625395
  • Kane JK, Hwang Y, Konu O, Loughlin SE, Leslie FM, Li MD (2005). Regulation of Homer and group I metabotropic glutamate receptors by nicotine. Eur J Neurosci. 21(5):1145-54. PMID: 15813924
  • Kane JK, Konu O, Ma JZ, Li MD (2004). Nicotine coregulates multiple pathways involved in protein modification/degradation in rat brain. Brain Res Mol Brain Res. 132(2):181-91. PMID:15582157
  • Konu* O, Xu* X, Ma JZ, Kane J, Wang J, Shi SJ, Li MD (2004). Application of a customized pathway-focused microarray for gene expression profiling of cellular homeostasis upon exposure to nicotine in PC12 cells. Brain Res Mol Brain Res. 121:102-13. *Equal contribution.  PMID:14969741
  • Li MD, Kane JK, Konu O (2003). Nicotine, body weight and potential implications in the treatment of obesity. Curr Top Med Chem. 2003;3(8):899-919.  PMID:12678939
  • Li MD, Konu O, Kane JK, Becker KG (2002). Microarray technology and its application on nicotine research.  Mol Neurobiol. 25(3):265-85.  PMID:12109875
  • Konu O, Li MD (2002). Correlations between mRNA expression levels and GC contents of coding and untranslated regions of genes in rodents. J Mol Evol. 54(1):35-41.  PMID:11734896
  • Konu O, Kane JK, Barrett T, Vawter MP, Chang R, Ma JZ, Donovan DM, Sharp B, Becker KG, Li MD (2001). Region-specific transcriptional response to chronic nicotine in rat brain. Brain Res. 909(1-2):194-203.  PMID:11478936