Group Leader

Prof. Mehmet Öztürk, Ph.D.

Mailing Address

Bilkent University
Faculty of Science, B Building
Department of Molecular Biology and Genetics
06800 Ankara, TURKEY

Office

Science B 239

Telephone

Fax

+90-312-266 50 97

e-mail

 Research Interests

Click for Öztürk Lab Site

• Ozturk N, Erdal E, Mumcuoglu M, Akcali KC, Yalcin O, Senturk S, Arslan-Ergul A, Gur B, Yulug I, Cetin-Atalay R, Yakicier C, Yagci T, Tez M, Ozturk M. Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells. Proceedings of National Academy of Sciences USA 103:2178-2183, 2006.
• Benhaj K, Akcali KC, Ozturk M. Redundant expression of canonical Wnt ligands in human breast cancer cell lines.Oncol Reports15:701-707, 2006.
• Erdal E, Ozturk N, Cagatay T, Eksioglu-Demiralp E, Ozturk M. Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells. International Journal of Cancer 115:903-910, 2005.
• Voeltzel T, Morel AP, Rostan MC, Ji J, Chiodino C, Ponchel F, Vigouroux J, de Fromentel CC, Soussi T, Ozturk M. A new set of monoclonal antibodies directed to proline-rich and central regions of p53. Hybridomas & Hybridomics 23:287-292, 2004.
• Ugur H, Sayan AE, Ozdamar SO, Kanpolat Y, Ozturk M. Expression of TAP73 and DeltaNP73 in malignant gliomas. Oncology Reports 11:1337-1341, 2004.
• Irmak MB, Ince G., Ozturk M and Cetin-Atalay R. Acquired tolerance of hepatocellular carcinoma cells to selenium deficiency: a selective survival mechanism? Cancer Research 63: 6707-6715, 2003.
• Atalay A, Crook T, Ozturk M and Yulug UG. Identification of genes induced by BRCA1 in breast cancer cells. Biochemical and Biophysical Research Communications 299:839-846, 2002.
• Cagatay T and Ozturk M. p53 mutation as a source of aberrant  β-catenin accumulatıon in cancer cells. Oncogene 21:7971-7980, 2002.
• Yildiz E, Oztan A, Sar F, Pınarbaşı E, Cetin-Atalay R, Akkız H and Ozturk M. Molecular characterization of a full genome Turkish Hepatitis C virus 1b isolate (HCV-TR1): a predominant viral form in Turkey. Virus Genes 25: 169-177, 2002.
• Demir E, Babur O, Dogrusoz U, Gursoy A, Nisanci G, Cetin-Atalay R and Ozturk M. PATIKA: An integrated visula environment for collaborative construction and analysis of cellular pathways. Bioinformatics 18, 996-1003, 2002.
• Sayan BS, Ince G, Sayan AE and Ozturk M. NAPO as a novel apoptosis marker. Journal of Cell Biology 155: 719-24, 2001.
• Sayan E. Sayan BS and Ozturk M. Acquired expression of transcriptionaly active p73 in hepatocellular carcinoma. Oncogene 20:5111-5117, 2001.
• Yolcu E, Sayan BS, Yagci T, Cetin-Atalay R, Soussi T, Yurdusev N, Ozturk M. A monoclonal antibody against DNA binding helix of p53 protein.Oncogene 20:1398-401, 2001.
• Moyret-Lalle C, Lalle P, Pedeux R, Guillot C, Martel S, Magaud JP, Puisieux A and Ozturk M. Differential p21 expression after ionizing and UVC irradiation in EBV-transformed lymphoblastoid cells. Electronic Journal of Oncology 2: 1-10, 2000.
• Morel A.P., Unsal K., Cagatay T., Ponchel F., Carr B., and Ozturk M. p53 but not p16INK4a induces growth arrest in retinoblastoma-deficient hepatocellular carcinoma cells. Journal of Hepatology 33: 254-265, 2000.
• Cetin-Atalay R and Ozturk M. p53 mutations as fingerprints of environmental carcinogens. Pure and Applied Chemistry, 72: 995-999, 2000.
• Ozdag H, Tez M, Sayek I, Muslumanoglu M, Tarcan O, Icli F, Ozturk M, Ozcelik T. Germ line BRCA1 and BRCA2 gene mutations in Turkish breast cancer patients. European Journal of Cancer, 36: 2076-2082, 2000.
• Eroglu C, Yildiz E, Ozturk M and Pinarbasi E. A highly sensitive and specific enzyme-linked immunosorbent assay of antibodies to hepatitis C virus. Acta Virologica, 44: 29-33, 2000.
• Mazoyer S et al. The exon 13 duplication in the BRCA1 gene is a founder mutation present in geographically diverse populations. American Journal of Human Genetics, 67: 207-212, 2000.