Group Leader

Assist. Prof. Ali O. Güre, M.D., Ph.D.

Mailing Address

Bilkent University
Faculty of Science, B Building
Department of Molecular Biology and Genetics
06800 Ankara, TURKEY

Office

Science B 248

Telephone

+90-312-290 25 07

Fax

+90-312-266 50 97

e-mail

Research Interests

• Developing immune-assays for the early diagnosis of cancer and defining targets for cancer immunotherapy, constitutes one of the two major areas of research in my lab; the second being the characterization and manipulation of epigenetic aberrations common to subpopulations of various tumors.

Academic Degrees and Employment

Publications

• Spisek R, Kukreja A, Chen LC, Matthews P, Mazumder A, Vesole D, Jagannath S, Zebroski HA, Simpson AJ, Ritter G, Durie B, Crowley J, Shaughnessy JD Jr, Scanlan MJ, Gure AO, Barlogie B, Dhodapkar MV.  Frequent and specific immunity to the embryonal stem cell-associated antigen SOX2 in patients with monoclonal gammopathy.J Exp Med. 2007 Apr 16;204(4):831-40.
• Gure AO, Chua R, Williamson B, Gonen M, Ferrera CA, Gnjatic S, Ritter G, Simpson AJ, Chen YT, Old LJ, Altorki NK. Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer. Clin Cancer Res. 2005 Nov 15;11(22):8055-62.
• Vural B, Chen LC, Saip P, Chen YT, Ustuner Z, Gonen M, Simpson AJ, Old LJ, Ozbek U, Gure AO. Frequency of SOX Group B (SOX1, 2, 3) and ZIC2 antibodies in Turkish patients with small cell lung carcinoma and their correlation with clinical parameters. Cancer. 2005 Jun 15;103(12):2575-83.
• Gure AO, Wei IJ, Old LJ, Chen YT. The SSX gene family: characterization of 9 complete genes. Int J Cancer. 2002 Oct 10;101(5):448-53.